Development of Neural Tube – MCQs
1. The neural tube is derived from which germ layer?
Mesoderm
Endoderm
Ectoderm
Neural crest
2. Neurulation begins approximately on which day of development?
Day 10
Day 14
Day 18
Day 28
3. Fusion of neural folds begins in which region?
Cranial region
Caudal region
Cervical region
Lumbar region
4. Anterior neuropore normally closes on:
Day 21
Day 23
Day 25
Day 30
5. Failure of anterior neuropore closure results in:
Spina bifida
Anencephaly
Meningocele
Syringomyelia
6. Secondary neurulation contributes to formation of:
Cerebral hemispheres
Brainstem
Caudal spinal cord
Thalamus
7. Neural crest cells arise from:
Roof plate
Neural folds
Floor plate
Basal plate
8. The sulcus limitans separates:
Roof and floor plates
Gray and white matter
Alar and basal plates
Neural tube and notochord
9. Motor neurons develop from:
Alar plate
Roof plate
Basal plate
Neural crest
10. Sensory neurons of spinal cord develop from:
Basal plate
Alar plate
Floor plate
Notochord
11. Which vitamin deficiency increases neural tube defect risk?
Vitamin B12
Vitamin D
Folic acid
Vitamin A
12. Central canal of spinal cord develops from:
Neural crest
Mantle layer
Lumen of neural tube
Mesoderm
13. Mantle layer of neural tube forms:
White matter
Gray matter
Ependyma
Pia mater
14. Posterior neuropore normally closes by:
Day 23
Day 25
Day 27
Day 35
15. Spina bifida occulta results from failure of:
Neural tube closure
Vertebral arch formation
Notochord regression
Alar plate development
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